STUDY ON ADENOVIRUS TYPE 1 INFECTION
نویسندگان
چکیده
منابع مشابه
Mouse adenovirus type 1 infection in SCID mice: an experimental model for antiviral therapy of systemic adenovirus infections.
The importance of human adenovirus infections in immunocompromised patients urges for new and adequate antiadenovirus compounds. Since human adenoviruses are species specific, animal models for systemic adenovirus infections rely on a nonhuman adenovirus. We established mouse adenovirus type 1 (MAV-1) infection of BALB/c SCID mice as a model for the evaluation of antiadenovirus therapy. In vitr...
متن کاملContribution of a Single Host Genetic Locus to Mouse Adenovirus Type 1 Infection and Encephalitis
UNLABELLED Susceptibility to mouse adenovirus type 1 (MAV-1) is mouse strain dependent; susceptible mice die from hemorrhagic encephalomyelitis. The MAV-1 susceptibility quantitative trait locus Msq1 accounts for ~40% of the phenotypic (brain viral load) variance that occurs between resistant BALB/c and susceptible SJL mice after MAV-1 infection. Using an interval-specific congenic mouse strain...
متن کاملSJL/J mice are highly susceptible to infection by mouse adenovirus type 1.
Mouse adenovirus type 1 (MAV-1) targets endothelial and monocyte/macrophage cells throughout the mouse. Depending on the strain of mouse and dose or strain of virus, infected mice may survive, become persistently infected, or die. We surveyed inbred mouse strains and found that for the majority tested the 50% lethal doses (LD(50)s) were >10(4.4) PFU. However, SJL/J mice were highly susceptible ...
متن کاملSevere Pneumonia Associated with Adenovirus Type 55 Infection, France, 2014
9 cells/L, a hemoglobin level of 86 g/L, and a leukocyte count of 8.28 × 10 9 cells/L with 17% neutro-phils and 78% lymphocytes. The patient was given symptomatic supportive treatment , methylprednisolone sodium succinate, and 5 g of γ-globulin. He was not given any antimicrobial drugs. On August 4, he was discharged from hospital after symptoms had resolved. In conclusion, our results confirm ...
متن کاملNew human adenovirus (candidate adenovirus type 35) causing fatal disseminated infection in a renal transplant recipient.
An antigenically distinct adenovirus is described which was isolated in March 1973 from the lungs and kidney of a 61-year-old woman who died of diffuse interstitial adenovirus pneumonia 55 days after receiving a cadaveric renal allograft. Complement fixation, hemagglutination inhibition, and serum neutralization tests on sequential serum specimens from the patient confirmed that the adenovirus ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Uirusu
سال: 1973
ISSN: 0042-6857,1884-3433
DOI: 10.2222/jsv.23.125